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Arizona Cardinals at Tennessee Titans Tips - Titans to win by 1-13 points

  • NFL Week 1 game scheduled at Nissan Stadium in Nashville on Sunday (18:00 BST)
  • The Cardinals posted a 1-1 record in the pre-season
  • The Titans went 2-1 in the pre-season
  • The Titans lost in the AFC Wildcard Play-offs last season
  • The Cardinals and Titans clash for the first time since 2017
The Titans take on the Cardinals at Nissan Stadium on opening week. (Frederick Breedon/Getty Images)
This is far and away the most intriguing game of the early slate between two genuine playoff contenders.

The Titans have been a popular Super Bowl smoky pick after adding Julio Jones to the receiving corps during free agency, while the Cardinals remain one of the most exciting offensive teams in the league behind Kyler Murray and DeAndre Hopkins.

Defensively, there is a bit of a query on the Titans, but their high-powered offence more than makes up for it after finishing fourth in the league in points scored last year.

These two sides don’t meet very often, which makes this a tough cross-conference game to try and pick.


The Cardinals certainly have enough talent to hang tough but given their troubles defending the run last year and their sub-par 4-4 record on the road, the edge belongs with Tennessee.

Best Bet: Cardinals 1-13 Winning Margin $2.50 at Neds - 1 Unit
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    Cardinals 1-13
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06 December 2021

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