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San Francisco 49ers at Detroit Lions Tips - 49ers to cover line

  • NFL Week 1 game scheduled at Ford Field, Detroit on Sunday (18:00 BST)
  • The 49ers went 2-1 in the pre-season
  • The Lions went winless in 3 pre-season games
  • This is the first encounter between the 49ers and Lions since 2018
Ford Field
The Lions host the 49ers in NFL Week 1. (Rey Del Rio/Getty Images)
A new era in Detroit officially kicks off on Monday as Jared Goff makes his first start in place of Matthew Stafford.

Ironically, Goff will square off against his old rival Jimmy Garoppolo, who was finally named San Francisco’s starting quarterback earlier in the week over rookie Trey Lance.

The jury is still out on whether either quarterback will succeed this year, which makes this a very tough game to bet on (and get excited about).

For San Francisco, people seem to forget this is a team that led the Chiefs in the Super Bowl only two years ago.

The Niners won only six games last year to finish last in the NFC West, but it’s hard to read too much into that considering Garoppolo was hurt alongside star tight end George Kittle.

As for Detroit, well let’s just say another Top 10 pick in the draft appears likely.

The Lions have lost star receiver Kenny Golladay to free agency, and based on Jared Goff’s accuracy issues last year, it’s hard to find too much confidence in the offence.


Ideally, San Francisco’s defence should do the talking with Nick Bosa back in the fold and make this a long day for a very average Detroit team.

Best Bet: 49ers -7.5 To Win $1.94 at Neds - 1 Unit
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    49ers -7.5
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06 December 2021

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