49ers Pick

Seattle Seahawks at San Francisco 49ers Tips - Back 49ers to cover

01 Oct 2021
  • NFL Week 4 fixture will take place at Levi's Stadium in Santa Clara on Sunday (21:05 BST)
  • The Seahawks (1-2) have dropped their last two games
  • The 49ers (2-1) are also coming off a loss
  • Seattle won both meetings against San Francisco last season
Levi's Stadium
The Seahawks visit the 49ers at Levi's Stadium in Week 4. (Photo by Ezra Shaw/Getty Images)
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San Francisco 49ers and Seattle Seahawks find themselves in the bottom two spots in the ultra-competitive NFC West. Needless to say, this could be an early season-defining encounter for both sides.

The 49ers opened their campaign with wins over battlers the Lions (41-33) and Eagles (17-11), but they were sunk by a late field goal against the Packers last week after hauling in a 17-0 deficit.

The Seahawks started solidly with a 28-16 win over the Colts, but since then they were pipped in overtime by the Titans (33-30) and sunk to a dismal 30-17 loss to the Vikings. The Seattle secondary has fallen apart in the past fortnight

The Seahawks have dominated this rivalry over the past decade, winning 13 of the teams’ past 15 clashes. Last season they prevailed 37-27 at home and 26-23 at Levi’s Stadium, with Russell Wilson chalking up six TD passes across the two victories.


The Niners have shown enough so far in 2021 to get behind them as only a narrow favourite here, with the struggling Seahawks’ secondary negating any advantage the Wilson v Garoppolo battle may give the visitors.

Best Bet: 49ers -2.5 Line @9/11 at Paddy Power - 1 Unit
49ers -2.5
@9/11 - 1 Unit
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